Estimating Time to ESRD in Children

1
Chronic Kidney Disease cause:* This field is required.
GLOMERULAR (e.g., focal segmental glomerulosclerosis [FSGS], systemic immunologic disease, hemolytic uremic syndrome [HUS])
NONGLOMERULAR (e.g., aplastic/hypoplastic/dysplastic kidney, obstructive uropathy, reflux nephropathy)
2
GFR (ml/min|1.73m²):* This field is required.Select the GFR or KDIGO classification (GI to GIV) for the child.
≥ 90 (GI)
60-89 (GII)
45-59 (GIIIa)
30-44 (GIIIb)
15-29 (GIV)
3
UPCR (mg/mg):* This field is required.Select the Urine Protein to Creatinine ratio.
< 0.5
0.5 - 2.0
> 2.0
4
PROGNOSIS:

GROUP A - NONGLOMERULAR CAUSE

Percentile for Prognosis Time to ESRD (years)

50th* >10

25th >10

10th 5.1 (95% CI: 4.2, 6.1)

* Interpretation: 50% of children with this profile will have had ESRD or 50% reduction in GFR by >10 years.
5
PROGNOSIS:

GROUP A - GLOMERULAR CAUSE

Percentile for Prognosis Time to ESRD (years)

50th* >10

25th 5.8 (95% CI: 4.5, 7.1)

10th 2.9 (95% CI: 2.3, 3.6)

* Interpretation: 50% of children with this profile will have had ESRD or 50% reduction in GFR by >10 years.
6
PROGNOSIS:

GROUP B - NONGLOMERULAR CAUSE

Percentile for Prognosis Time to ESRD (years)

50th* >10

25th 5.5 (95% CI: 4.7, 6.4)

10th 2.8 (95% CI: 2.3, 3.3)

* Interpretation: 50% of children with this profile will have had ESRD or 50% reduction in GFR by >10 years.
7
PROGNOSIS:

GROUP B - GLOMERULAR CAUSE

Percentile for Prognosis Time to ESRD (years)

50th* 6.2 (95% CI: 4.9, 7.5)

25th 3.2 (95% CI: 2.5, 3.8)

10th 1.6 (95% CI: 1.3, 2.0)

* Interpretation: 50% of children with this profile will have had ESRD or 50% reduction in GFR by 6.2 years.
8
PROGNOSIS:

GROUP C - NONGLOMERULAR CAUSE

Percentile for Prognosis Time to ESRD (years)

50th* 7.4 (95% CI: 5.8, 9.0)

25th 3.7 (95% CI: 2.9, 4.6)

10th 1.9 (95% CI: 1.5, 2.3)

* Interpretation: 50% of children with this profile will have had ESRD or 50% reduction in GFR by 7.4 years.
9
PROGNOSIS:

GROUP C - GLOMERULAR CAUSE

Percentile for Prognosis Time to ESRD (years)

50th* 4.2 (95% CI: 3.2, 5.2)

25th 2.1 (95% CI: 1.6, 2.7)

10th 1.1 (95% CI: 0.8, 1.4)

* Interpretation: 50% of children with this profile will have had ESRD or 50% reduction in GFR by 4.2 years.
10
PROGNOSIS:

GROUP D - NONGLOMERULAR CAUSE

Percentile for Prognosis Time to ESRD (years)

50th* 4.0 (95% CI: 3.1, 4.8)

25th 2.0 (95% CI: 1.6, 2.5)

10th 1.0 (95% CI: 0.8, 1.3)

* Interpretation: 50% of children with this profile will have had ESRD or 50% reduction in GFR by 4 years.
11
PROGNOSIS:

GROUP D - GLOMERULAR CAUSE

Percentile for Prognosis Time to ESRD (years)

50th* 2.3 (95% CI: 1.7, 2.8)

25th 1.1 (95% CI: 0.8, 1.5)

10th 0.6 (95% CI: 0.4, 0.7)

* Interpretation: 50% of children with this profile will have had ESRD or 50% reduction in GFR by 2.3 years.
12
PROGNOSIS:

GROUP E - NONGLOMERULAR CAUSE

Percentile for Prognosis Time to ESRD (years)

50th* 2.7 (95% CI: 2.3, 3.2)

25th 1.4 (95% CI: 1.1, 1.7)

10th 0.7 (95% CI: 0.6, 0.9)

* Interpretation: 50% of children with this profile will have had ESRD or 50% reduction in GFR by 2.7 years.
13
PROGNOSIS:

GROUP E - GLOMERULAR CAUSE

Percentile for Prognosis Time to ESRD (years)

50th* 1.6 (95% CI: 1.2, 1.9)

25th 0.8 (95% CI: 0.6, 1.0)

10th 0.4 (95% CI: 0.3, 0.5)

* Interpretation: 50% of children with this profile will have had ESRD or 50% reduction in GFR by 1.6 years.
14
PROGNOSIS:

GROUP F - NONGLOMERULAR CAUSE

Percentile for Prognosis Time to ESRD (years)

50th* 1.3 (95% CI: 1.0, 1.7)

25th 0.7 (95% CI: 0.5, 0.9)

10th 0.3 (95% CI: 0.2, 0.4)

* Interpretation: 50% of children with this profile will have had ESRD or 50% reduction in GFR by 1.3 years.
15
PROGNOSIS:

GROUP F - GLOMERULAR CAUSE

Percentile for Prognosis Time to ESRD (years)

50th* 0.8 (95% CI: 0.5, 1.0)

25th 0.4 (95% CI: 0.3, 0.5)

10th 0.2 (95% CI: 0.1, 0.3)

* Interpretation: 50% of children with this profile will have had ESRD or 50% reduction in GFR by 0.8 year or 9 months.
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Please recheck the values.

Estimates not available due to infrequent patient profile:

GFR >90

and

UPCR 0.5-2.0 or >2.0
Should be Empty:

Percentile for Prognosis	Time to ESRD (years)
50th*	>10
25th	>10
10th	5.1 (95% CI: 4.2, 6.1)